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Question:

You are going to be hauling hazardous materials over a route you do not know well. When should you check the route and the permits needed for the trip?

A Before starting the trip.
Explaination

Some states and counties require permits to transport hazardous materials or wastes. They may limit the routes you can use. Local rules about routes and permits change often. It is your job as driver to find out if you need permits or must use special routes. Make sure you have all needed papers before starting.