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Question:

As the blood alcohol concentration (BAC) goes up, what happens?

A Judgment and self-control are affected.
Explaination

Alcohol affects more and more of the brain as BAC builds up. The first part of the brain affected controls judgment and self-control. One of the bad things about this is it can keep drinkers from knowing they are getting drunk. And, of course, good judgment and self-control are absolutely necessary for safe driving.