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Question:

You have loaded a hazardous material into a cargo tank. What must you do before you move the vehicle?

A Close all manholes and valves and be sure they are free of leaks.
Explaination

Close all manholes and valves before moving a tank of hazardous materials, no matter how small the amount in the tank or how short the distance. Manholes and valves must be closed to prevent leaks. It is illegal to move a cargo tank with open valves or covers unless it is empty according to CFR, Title 49 section 173.29.