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You are hauling hazardous materials, and you find that one of your tires is leaking. You must

A stop at the nearest safe place and fix it.

Don't risk an accident from a flat tire, especially when carrying hazardous materials. If you have a leaking or flat tire, don't drive except to the nearest safe place to fix it. Note: The rules on parking placarded vehicles apply even if you park to fix or replace a tire. For example, if you're carrying explosives, you can't park (to fix a tire or for any other reason) within 300 feet of any place where people gather.