Where in the trailer could you place cargo so that the weight applied to the trailer tandems is greater than the weight of the cargo itself?

Because the trailer pivots up and down at the kingpin above the drive axles, the floor of the trailer acts as a lever pushing down against the trailer tandems when freight is loaded into the overhang portion of the trailer. The further back you load the freight into the overhang portion of the trailer, the more leverage it creates. The net effect of this leverage is that you're putting more weight on the trailer tandems than the cargo itself weighs, and you will actually take a little bit of weight off the drive axles at the same time.