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Can a bus carry 100 pounds each of class 1, class 3, class 4, and class 5 hazardous materials?

A Yes.

Passenger buses can carry up to 100 pounds of each class of hazardous materials and up to 500 pounds total. However, there are some exceptions. Division 2.3 (poison gas) and liquid Class 6 (poison) cannot be carried in any amounts. Explosives and radioactive cannot be carried in the passenger area.